LAA Closure

LAA Closure

A one-time Solution for Reducing the Risk of Stroke

The WATCHMAN LAA Closure devices offer a proven safe and effective option for reducing the risk of stroke in non-valvular AF patients.

  • WATCHMAN FLX is the next generation LAA closure device and is built on the proven clinical platform of WATCHMAN.
  • Closing the left atrial appendage reduces the risk of stroke as well as the long-term risk of bleeding which is associated with OAC in patients with non-valvular AF.
  • Long-term data from PROTECT-AF and PREVAIL demonstrated that WATCHMAN offered statistically significant reductions in disabling and fatal stroke, non-procedure-related major bleeding and mortality compared to warfarin after 5 years of follow-up.1
  • The PINNACLE FLX US IDE Clinical Trial showed WATCHMAN FLX safety and efficacy, meeting the primary safety endpoint with an 0.5% procedure-related event-rate and a primary endpoint of 100% effective closure rate at 12 months.2


WATCHMAN is the most studied LAA Closure device worldwide and is the only with proven safety, efficacy, and patient benefits from both randomised trials and multicentre registries

> 6,800
patients studied in clinical trials

> 11,000
patient-years follow-up

GLOBAL
reach

Proven Procedure

Learn about the efficacy results of WATCHMAN in clinical trials of patients with non-valvular AF, eligible or with contraindication to OAC therapy

Proven Procedure

Proven Safety

Review safety data from clinical studies and real-life registries

Proven Safety

REFERENCES
* In non-valvular AF Patients
1. Reddy VY, 5-Year Outcomes After Left Atrial Appendage Closure From the PREVAIL and PROTECT AF Trials. J Am Coll Cardiol. 2017 Dec 19;70(24):2964-2975.
2. Doshi SK, et al. PINNACLE FLX Results Presented at HRS 2020.

CAUTION:
The law restricts these devices to sale by or on the order of a physician. Indications, contraindications, warnings and instructions for use can be found in the product labelling supplied with each device.
Products shown for INFORMATION purposes only and may not be approved or for sale in certain countries.
This material not intended for use in France.